Polyoxyl 40 Hydrogenated Castor Oil contains mainly the tri-hydroxystearate ester of ethoxylated glycerol, with smaller amounts of polyethylene glycol tri-hydroxystearate and of the corresponding free glycols. Common Chemistry. Description SDS Pricing . VitiPure HCO 40 is obtained by reacting 40 moles of ethylene oxide with 1 mole of hydrogenated castor oil. . Polyoxyl 40 hydrogenated castor oil 1 - 6.5 moles ethoxylated . The aim of the present study was to develop an optimized Genkwanin (GKA)-loaded self-nanoemulsifying drug delivery system (SNEDDS) formulation to enhance the solubility, intestinal permeability, or. i. Inxight Drugs. Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Acute Mammalian Toxicity. CAS 61788850 UNII 7YC686GQ8F SYNONYMS. Systemic Toxicity/Organ Effects incl. If you want to request a quotation or place an order, please instead add the desired products to your cart and then request a quotation or order from the cart. 40. i. MPNS; NCBI Taxonomy. 190 / Kg. When adding PEG 40 Hydrogenated Castor Oil to cosmetics formulations, it can be blended in its cold state directly into the oil phase at a suggested ratio of 3:1 (PEG 40 Hydrogenated Castor Oil to oil). Tween 80 has single chian of oleic acid as lipophilic part while cremophore surfactants have three fatty acid chain attahced to PEG-glycerol. Congealing temperature : 200c to 300C. CAS: 61788-85-. CAS No. Abstract The aim was to develop a nanocarrier based on polyoxyl 15 hydroxystearate . At the room temperature it appears as white to yellowish . You can also browse global suppliers,vendor,prices,Price,manufacturers of Polyoxyl 40 Hydrogenated Castor Oil USP/NF/EP(). Polyoxyl 60 hydrogenated castor oil free nanosomal formulation of immunosuppressant Tacrolimus: pharmacokinetics, safety, and tolerability in rodents and humans. Polyoxyl 40 Hydrogenated Castor Oil containsadd 50 mL of ethyl acetate, shake vigorously for 2 minutes, and mainly the tri-hydroxystearate ester of ethoxy-allow to separate as before. Polyoxyl Hydogenated Castor Oil / Kolliphor RH40) to address your drug development and formulation challenges (e.g. 3524 NF Monographs: Polyoxyl 40 Stearate. AT. developmental neurotoxicity. CAS: 61788-85- MDL: MFCD01771439 Synonyms: Polyethylene glycol castor oil hydrogenated, Ethoxylated hydrogenated castor oil, Kolliphor RH, Cremophor RH, Macrogolglycerol hydroxystearate, PEG castor oil, Polyoxyl hydrogenated castor oil Polyethylene Glycol 40 Castor Oil, Hydrogenated is a polyether compound that is used in a wide variety of fields including pharmaceutical manufacturing as . . Justia Patents US Patent Application for METHODS OF MAKING STABLE SILK FIBROIN FORMULATIONS Patent Application (Application #20220331400) It is the polyethylene glycol derivatives of hydrogenated castor oil, and it functions as a surfactant, a solubilizer, an emulsifier . Sort by Relevance. Specifically, the invention provides a pharmaceutical formulation of a gelled nanoemulsion, with a concentration of glycyrrhetinic acid comprising from 0.001% to 30% w/w (percentage by weight). ST. A combination of synthetic polyethylene glycol (PEG) obtained by catalytic hydrogenation of chemically produced castor oil using an ethoxylation process with a chemical reaction in which ethylene oxide is added to a castor oil substrate. Applications Products Services Support. Polyoxyl castor oil. It contains principally 12-hydroxystearic acid. PEG-40 Hydrogenated Castor Oil is the polyethylene glycol (PEG) derivative of hydrogenated castor oil. Full addition of water will decrease the viscosity . Container. All capsule strengths also contain DL-alpha-tocopheryl acetate (Vitamin E), phytosterol esters, polyoxyl 40 hydrogenated castor oil, and propylene glycol monolaurate as inactive . PEG 40 Castor Oil is a slightly viscous amber colored liquid. Polyoxyl 40 Hydrogenated Castor Oil or Macrogolglycerol Hydroxystearate also referred to as Cresol RH 40: CAS Number: 61788-85-0, EINECS EC Number: 500-147-5, Molecular Formula: yy, Molecular Weight: yy, HS Code ---** How big is your requirement or how small We serve it all. Hydroxyl value : 60 - 80. It is almost tasteless when used in oral preparations. ST. EINECS: 500-151-7. Polyoxyl 40 hydrogenated castor oil, Propylene glycol, Trolamine, Water. E. Endocrine Activity. Prakash Trading Company. Polyoxyl 40 hydrogenated castor oil is a non-ionic solubilizer and emulsifying agent that is obtained by reacting hydrogenated castor oil with ethylene oxide . Be the first to review "Polyoxyl 40 Hydrogenated Castor Oil USP/NF/EP" Cancel reply. drug delivery, bioavailability, stability, solubility, etc.) All Photos (1) [41,42] Rachmawati et al. $ 83.20. . Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo [1]. PEG-40 Hydrogenated Castor Oil is is an amber colored, slightly viscous liquid that has a naturally mildly fatty odor. VitiPure HCO 40 is versatile non-ionic solubilizer and emulsifier enhancing the solubility and bioavailability of hydrophobic APIs and fat-soluble vitamins. Polyoxyl 40 hydrogenated castor oil 25% will solubilize vitamin A palmitate 88 mg/mL or vitamin A propionate 160 mg/mL. Hydroalcoholic preparations of this material produce foam, which can be reduced by adding polypropylene glycol 2000. Color : White / transparent. Maint. Compare Product No. : MFCD01771439 Flash Point (F): 467.6 F Flash Point (C): 242 C Packaging and storage Preserve in tight containers. PEG 40 HYDROGENATED CASTOR OIL SOLUBILITY. for Polyoxyl 40 Hydrogenated Castor Oil. 6" residual fuel oil as defined by ASTM D396-95 Standard Specification for Fuel Oils . This report reviews the safety data on these ingredients. Shriji Chemical. Oleic acid and linoleic acid are the other significant components. 61791-12-6) and PEG-30 and -40 Hydrogenated Castor Oil (generic CAS No. CHEMISTRY De nition and Structure PEG-30, -33, -35, -36, and -40 Castor Oil (generic CAS No. Emulsifier is a specific type of surfactant which allows two liquids to mix together evenly. 3528 NF Monographs: Polysorbate 80. It has the empirical formula of C 30 H 48 O 3 and a molecular weight of 456.7 g/mol. PEG 40 Hydrogenated Castor Oil is the polyethylene glycol derivatives of hydrogenated castor oil, and is an amber colored, slightly viscous liquid that has a naturally mildly fatty odor. i. GRIN. acute toxicity of polyoxyl 25 hydrogenated castor oil, polyoxyl 40 hydrogenated castor oil, polyoxyl 60 hydrogenated castor oil were reported to be very low with LD 50 values of more than 5000 mg/kg body weight in rats. Additional information. Manufacturers: MUBY CHEMICALS Ambernath Mumbai, Ankleshwar Gujarat, India TEL: (OFFICE) +912223770100, +912223726950 Current Date Time in India GMT+5:30. e-mail: info@mubychem.com Molecular Formula: N/A. i. NCATS GSRS Full Record. Company Information . Molecular Weight: 0.00. 6. Polyoxyl 35 castor oil and polyoxyl hydrogenated castor oil were judged slightly irritating when wherein the basic amino acid is present in an amount corresponding to 0.01 to 2 wt % of the total composition weight, the weight of the basic amino acid being calculated as free base form; b. an effective amount of a preservative selected from methylisothiazolinone (MIT), . and hydrogenated castor oil (q.v.) Polyoxyl 40 Hydrogenated Castor Oil. ethoxylated. . Appearance: whitish / yellow liquid. Iodine value : NMT 2%. Such as Acrysol K-140, Cremophor RH40, Kolliphor RH40, Polyoxyl 40 Hydrogenated Castor Oil, our product Orynophor PH40 as per USP is a Castor Oil Derivatives used as a nonionic solubilizers and emulsifiers for the manufacture of cosmetic & pharmaceutical products. Chemical Numbering System. : 61788-85-. Kolliphor RH 40; CAS Number: 61788-85-0; Synonyms: Cremophor RH 40,Macrogolglycerol hydroxystearate,PEG-40 castor oil,Polyoxyl 40 hydrogenated castor oil; find Sigma-Aldrich-07076 MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich. Products with the EWG VERIFIED mark have met the program's impurity and use restrictions based on EWG's review of the company's data. Glyceryl Palmitostearate. Polyethylene glycols (PEGs) are a mixture of polymers combined with glycol to form a thick liquid. 3526 NF Monographs: Polysorbate 40. SIMFORT Hair Treatment for Men & Women, Recommended for Use with SIMFORT Carbonic Acid Shampoo , 4.2oz, $50.00 PLENTY OF 3 ACTIVE INGREDIENTS: Ginger root extract, sugar cane extract and. Hco -10 Hydrogenated Ethoxylate Castor Oil. 3530 USP Monographs: Polyvinyl Alcohol. CASRN: 61791-12-6. i. DailyMed Regulated Products. [43] evaluated the safety of using a large amount of polyoxyl 40 hydrogenated castor oil as a surfactant in oral nanoemulsion formulations. i. NCI Thesaurus. In some industries it may go by the name of PEG 2000, with 2000 indicating the average molecular weight. Suggest One No specific molecular structure known for this excipient. PEG-60 hydrogenated castor oil is a nonionic surfactant used as an emulsifying and solubilising agent in pharmaceutical preparations and cosmetics. Peg 40 Hydrogenated Castor Oil. PEG-40 Hydrogenated Castor Oil is a brittle and hard vegetable wax. Basic component: . Find polyoxyl 40 castor oil and related products for scientific research at MilliporeSigma. A clear yellow viscous liquid or semi-solid, freely soluble in water. This product is a surfactant based on renewable vegetable raw materials. i. USDA Plant. Drain the lower, aqueous phase It can be used as Vitamin Solubilizer, Oil & Perfume Solubilizer, API Solubilizer . PEG-40 hydrogenated castor oil is a nonionic surfactant used as an emulsifying and solubilising agent in pharmaceutical preparations and cosmetics. Castor oil is a vegetable oil pressed from castor beans. It results from the reaction of glycerol tri-hydroxystearate with about 40 to 45 moles of ethylene oxide. 3525 NF Monographs: Polysorbate 20. The different formulations are designed for the treatment of the different conditions on which the drug is known to have a therapeutic effect. Form. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. It results from the reaction of glycerol tri-hydroxystearate with about 40 to 45 moles of ethylene oxide. POLYOXYL 40 HYDROGENATED CASTOR OIL NF (30-4996) View SDS. Systemic Toxicity/Organ Effects-Single Exposure. Sodium Lactate. Properties and applications. It can be used to emulsify fatty acids and alcohols. Ethylene Glycol Monostearate. If the formula is cloudy, the amount of PEG 40 Hydrogenated Castor Oil may be increased for enhanced . PEG-35 Castor oil; PEG-36 Castor oil; PEG-40 Castor oil; PEG-44 Castor oil; PEG . Its boiling point is 313 C (595 F) and its density is 0.961 g/cm 3. 3529 NF Monographs: Polyvinyl Acetate Phthalate. CAS No. A fine, almost white to pale yellow powder, practically insoluble in water, m.p. It includes a mixture of triglycerides in which about 90% of fatty acids are ricinoleates. Molecular Weight: N/A. Mix vitamin with Poly Oxyl 40 Hydrogenated Castor Oil and heat up to 600 to 650C. It is faster, cheaper, and you will be able to benefit from the available discounts and other advantages. The physico-chemical properties (waxy solid, low water solubility and log Pow > 6) and the molecular weight (>1000 g/mol) of Castor oil, hydrogenated, ethoxylated are in a range suggestive of low absorption through the skin. POLYOXYL 40 HYDROGENATED CASTOR OIL [MART.] the not so good: here are some concerns about the ethoxylation process that is used to manufacture this ingredient. i. ITIS. The active substance content is close to 100%. Based on the available data it is therefore concluded that PEGs of a wide molecular weight range (200 to over 10,000), their ethers (laureths, ceteths . The disclosure features non-irritating pharmaceutical compositions containing CD101 in pharmaceutical acceptable salt (e.g., CD101 acetate) or neutral form. 50 Mol Hydrogenated Castor Oil. Heat water at the same temperature. : currently ok. . 61788-85- - Polyoxyl 40 hydrogenated castor oil [NF] - Similar structures search, synonyms, formulas, resource links, and other chemical information. GB EN. As previously reported, nearly 20% of PEG-40 hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to the aqueous phase. the good: As an emollient, PEG-40 hydrogenated castor oil can help reduce the appearance of dry flaky skin. It is a colourless or pale yellow liquid with a distinct taste and odor. POLYOXYL 40 HYDROGENATED CASTOR OIL Unresolved Excipient Suggest One No . Polyoxyl 35 castor oil | C63H116O15 | CID 154733643 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological . Technical Information: Name: PEG-40 Hydrogenated castor oil Formula: CH2CH2O Molecular Weight: No CAS: 61788-85- UN no: Cetostearyl Ether to a suitable glass bottle of about 60-mL ca- lar weight gradients within it, and transfer 200 L to a 5- . 4 Physical and Chemical Properties Physical and chemical properties of PEG-30, -33, -35, -36, -40 castor oil and PEG-30 and -40 hydrogenated castor oil can be found in the original safety assessment.1 A supplier reports that PEG-30,-35, and-40 are pale yellow viscous liquids at 30 C and have a maximum water content of 0.2%.4 PEG-40 hydrogenated castor oil is reported SIMFORT Hair Treatment / Sparkling Scalp Shampoo - health and beauty. . Application: Multifunctional agent, which is used as an emulsifier, surfactant and solvent. ZINC ID(s) Availability Present in 0 ZINC catalogs Known Active Genes . SELF-EMULSIFYING FORMULATIONS OF DIM-RELATED INDOLES: : US15094732: : 2016-04-08: (): US20170014382A1: (): 2017-01-19: : B Studies have found PEG-40 to be safe in concentrations of up to 100%. . Tips, Tricks, and Quirks: PEG-40 Hydrogenated Castor Oil has the coolest stringy-gooey consistency! Next, this can be added to the water phase. Discover the latest developments on Polyoxyl 40 Hydrogenated Castor Oil Pharma Excipients used in Drug Delivery Systems (DDS) on PharmaCompass. Rating : 6.8. Castor oil, hydrogenated, ethoxylated is a waxy solid with a vapour pressure of < 1E-6 Pa at 20 C (calculated 1.17 . . Packaging: drums. Contact Supplier. Polyoxyl Castor oil; Castor oil polyoxyethylene ether; Castor oil, ethoxylated; . Polyoxyl 40 Hydrogenated Caster Oil. 1119.6338; All; Links to Resources; Names & Synonyms; Registry Numbers; Toxicity * denotes mobile formatted website. 3527 NF Monographs: Polysorbate 60. UNIIs are generated based on scientific identity characteristics using ISO 11238 data elements . As a result of hydration, the viscosity will increase after addition of around 50% water. weather in flagstaff arizona. This study showed that . that are used in a variety of cosmetic products. Synonym(s): Cremophor RH 40, Macrogolglycerol hydroxystearate, PEG-40 castor oil, Polyoxyl 40 hydrogenated castor oil. Technical inquiry about: 45-1547200 Polyoxyl 35 Castor Oil. Ethylene Glycol Distearate. Evaluation on the safety use of high concentration of polyoxyl 40 (PEG-40) hydrogenated castor oil as a surfactant for oral nanoemulsion was performed in Webster mice. 1 Litre. i. Note. Minimum Order Quantity: 100 Kg. PEG-40 has the FDA-approval for external use. Polyoxyl 35 castor oil, appearance: pale yellow, oily liquid at temperatures above 26C ; HLB: 12 - 14 ; Polyoxyl 40 hydrogenated castor oil, appearance: white to yellowish, semisolid paste at temperature above 30C The main constituent of this . Contact Supplier. immunotoxicity-Repeated Exposure. Structure. The pharmaceutical compositions can be intravenously administered to a subject to treat fungal infections (e.g., candidiasis) in the subject. Color : Consistency : thick liquid at 300C. Molecular Weight. Saponification value : 45 - 69. Storage & Shelf Life: Stored somewhere cool, dark, and dry, PEG-40 Hydrogenated Castor Oil should last about two years. . Advanced Search. Developmental Toxicity incl. convert decimal to fraction Weight: 25 g: Dimensions: 1 1 1 cm: Reviews There are no reviews yet. PDF | Antipsychotic drugs lead to numerous disabling side effects, and many are highly lipophilic, making them hard to formulate at high strength.. | Find, read and cite all the research you . With stirring ad water in mixtue of Poly Oxyl 40 Hydrogenated Castor Oil and vitamin. 83-88C. Also find out more about Polyoxyl 40 Hydrogenated Castor Oil Pharma Excipients' applications, manufacturers and distributors, prices, news, etc. Search for pharma excipients offered by BASF and find excipient solutions (e.g. US EN. A polyethylene glycol derivative of hydrogenated castor oil where the average PEG chain length is 40. DOT Classification: Land transport: USDOT: Not classified as a dangerous good under transport regulations Sea transport: IMDG: Not classified as a dangerous good under transport regulations Air transport: IATA/ICAO: Not classified as a . oil (q.v.) Molecular Formula & Molecular Weight. The aim was to confirm the safety of using high concentrations (~20%) of PEG-40 hydrogenated castor oil in the formula, especially when used long-term. ROKAcet KO400G (PEG-6 Glyceryl Cocoate) ROKAcet LPK (Alkoxylated fatty alcohol) ROKAcet HR40 is a non-ionic surfactant, INCI name: PEG-40 Hydrogenated Castor Oil. Thermodynamically stable and spontaneous nanoemulsion was formed by the . It doesn't strictly need to be melted to work with it, but that does make things easier. Packaging Size. Polyoxyl 40 Hydrogenated Castor Oil USP/NF/EP 0 out of 5 ( There are no reviews yet. ) what does blaza face look like. It is also used to improve the texture and sensory feel of formulations. Polyoxyl 40 castor oil. A: Dissolve about 0.1 g in 1 mL of water, add 9 mL of sodium chloride solution (1 in 20), and heat in a water bath: the solution becomes turbid at a temperature between 70 and 85 . Also, Cremophor RH40 (polyoxyl 40 hydrogenated castor oil) appeared to be less readily digested . PEG-40 hydrogenated castor oil is a polyethylene glycol derivative of castor oil; may be contaminated with potentially toxic impurities such as 1,4-dioxane. 61788- Include it in the heated oil phase. Specs. Its uses are common in this form as an emulsifier and a fragrance ingredient. Poly Oxyl 40 Hydrogenated Castor Oil is chemically polyoxyl 40 hydrogenated castor oil confirms to USP/NF/ EP specification. Registration dossier Castor oil (Ricinus communis . Hydrogenated castor oil. . Related Catalog. 3523 NF Monographs: Polyoxyl 40 Hydrogenated Castor Oil. Typical Specifications. 195 / Kg. Showing 1-1 of 1 result for " polyoxyl 40 hydrogenated castor oil. : 61788-85- Synonyms: Cremophor RH 40; Macrogolglycerol hydroxystearate; PEG-40 castor oil; Polyoxyl 40 hydrogenated castor oil MDL No. Physical and chemical data contained in this SDS are provided only for use in assessing the hazardous nature of the material. KLEEN HAND SANITIZER MANGO alcohol gel Product Information Product Type HUMAN OTC DRUG Item Code (Source) NDC:79741-003 Route of Administration TOPICAL Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Prepared by the reaction of castor oil with ethylene oxide. Visit ChemicalBook To find more Polyoxyl 40 Hydrogenated Castor Oil USP/NF/EP() information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Packaging Type. Molecular formula; Smiles; InChI; In addition, information on the type of substance, origin, number and type of registered compositions and other places where the substance is listed are displayed in this section. . Applications Products Services Support. PEG-40 hydrogenated Castor Oil : 26 .20 ; Nutegrit/M menhaden oil (60% Triglyceride Oil) 10.49 (minimum 5.25% DHA+EPA) Cremphore surfactants are more bulky and having higher molecular weight compare to Tween surfactants. Polyoxyl 40 Stearate. Liquid. SRM 1622e consists of 100 mL of commercial "No. The structural formula for testosterone undecanoate is presented in Figure 1. . TAGAT CH 40; Resources. PEG-150 Distearate. Valens Pharmachem Private Limited. . Rs 245 / Kg Get Latest Price. Generally speaking, PEGs are not skin irritants.
Les Eaux De Chanel Fragrantica, Glycolipids And Glycoproteins Function, Autistic Child Drinking A Lot, What Is A Syllabus In College, Double-entry Accounting Example,