"How do you find something if you're unsure of what to look for? As the long-awaited COVID-19 vaccine rollout begins across the country and everyone is eager to get back to normal life, it can be confusing to understand what you can and cannot do once you and those around you are vaccinated. Last medically reviewed on December 11, 2022. Some reports may have incomplete information. Physical therapy helped improve his range of motion to an extent, but his pain lingers. Tendonitis is found among people who get Pfizer BioNTech Covid Vaccine, especially for people who are female, 60+ old, and in the first week of getting the vaccine. Both programs are administered by the Health Resources and Services Administration (HRSA). While the connection between tinnitus and the Covid vaccine are not yet understood: The British Tinnitus Association has labeled tinnitus a rare side effect of the vaccine. A Baylor College of Medicine vaccine expert weighs in on . If a person has persistent joint pain after any infection, they should contact a doctor. 2023 eHealthMe.com. Smoking, older age, and preexisting joint pain had links to post-COVID-19 arthritis. But during the pandemic, many people's entire workday has been spent at home. Heart failure: Could a low sodium diet sometimes do more harm than good? This results when the injection site is too low or the needle is placed. According to the American Academy of Orthopaedic Surgeons, this is unlikely to occur. COVID-19 vaccines can cause mild side effects after the first or second dose, including: Pain, redness or swelling where the shot was given Fever Fatigue Headache Muscle pain Chills Joint pain Nausea and vomiting Swollen lymph nodes Feeling unwell Most side effects go away in a few days. All material on this website is protected by copyright. The phase IV clinical study analyzes which people get Pfizer BioNTech Covid Vaccine and have Tendonitis. "It's the patients who have persistent symptoms who are referred to orthopedic surgeons," Keeling said. Even if the vaccine is inadvertently injected into either of these spaces, studies have shown that it will have no harmful side effects. However, it is not known if the vaccine will cause a positive antibody test in patients who have been vaccinated but not had the virus. PMC Jackson and Noren said SIRVA attorneys advised that their injuries would not likely be compensated under the CICP. Opens in a new tab or window, Visit us on LinkedIn. The nasopharyngeal swab was negative for SARS-CoV-2 30 days after the first symptoms. To date, three published cases describe PTS after COVID-19 vaccination ( 4 - 6 ), but none include imaging to substantiate the diagnosis. One of these cases involves the ulnar nerve ( 4 ), which is rarely reported in PTS ( 1, 14 ). Tinnitus or ear ringing can happen after COVID-19 vaccines. 8600 Rockville Pike The report focuses on a 53-year-old man with a family history of RA. He or she may also recommend waiting for a period of time after vaccination.Your doctor can answer any questions you may have about the timing of corticosteroid injections and COVID-19 vaccination. The AAOS Patient Safety Committee recommends avoiding musculoskeletal corticosteroid injections for two weeks before and one week after COVID vaccine administration. Other Northwestern authors on the paper were Santhoshini Leela Ramani (Northwestern University medical student), Dr. Jonathan Samet (radiology), Dr. Colin Franz (PMR and neurology), Dr. Christine Hsieh (rheumatology), Dr Cuong Nguyen (dermatology) and Dr. Craig Horbinski (pathology). If you are allergic to polyethylene glycolone of the ingredients used in the COVID-19 vaccinethe CDC advises against being vaccinated. "We treat based on a full evaluation including history and physical findings, and imaging if needed," Kennedy said. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Usually, they start 16 weeks after an infection. If you have had an allergic reaction to another vaccine or to injectable medication, the CDC recommends that you consult your regular physician before receiving the COVID-19 vaccine. However, there are less frequent symptoms you probably wouldn't expect that follow some people both during the illness and long after recovery. ScienceDaily, 18 February 2021. * Approximation only. Different individuals may respond to medication in different ways. "One of the most common neurological symptoms in COVID patients, which can still persist after the initial disease, is loss of smell and taste sensation. You can use the study as a second opinion to make health care . Shoulder injury related to vaccine administration (SIRVA) is an uncommon event, but can occur after vaccination for SARS-CoV-2. "Radiological images confirm 'COVID-19 can cause the body to attack itself': Imaging illustrates severity, long-term prognosis of COVID-19-related muscle, joint pain." If you have an acute injurysuch as a sprain or broken bonebut you are not having surgery, there is no reason to delay vaccination. You can use the study as a second opinion to make health care decisions. They examined 100 people from Egypt who had recovered from COVID-19 several months prior. An infection with the SARS-CoV-2 virus may cause new or worse symptoms. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. All rights reserved. The Lancet Regional Health Southeast Asia, The Lancet Regional Health Western Pacific, Avoiding diagnostic pitfalls in children with musculoskeletal symptoms, Anti-SARS-CoV-2 mRNA vaccine in patients with rheumatoid arthritis, US Centers for Disease Control and Prevention. . Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. (Photo: Getty) getty. Federal government websites often end in .gov or .mil. All information is observation-only. The study is a retrospective review of data from patients who presented to Northwestern Memorial Hospital between May 2020 and December 2020. Bookshelf Some patients worry that receiving an injection in this area could permanently injure their shoulder. Since the COVID-19 vaccine does not contain live or attenuated virus material, it cannot give you the disease. According to a 2022 review, reactive arthritis may occur in genetically predisposed individuals 14 weeks after a variety of infections, including the respiratory virus SARS-CoV-2 and some infections of the digestive or urinary tract. In a 2021 study, researchers tried to gauge how common this is. If you've received monoclonal antibodies, you must wait 90 days after recovering from COVID-19 to receive the vaccine. However, a 2022 case report notes that some people have developed new or worse symptoms of autoimmune conditions after receiving the COVID-19 vaccine. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Reactive arthritis can occur after various infections, even if joint pain was not a symptom during the initial illness. Coronavirus disease 2019 (COVID-19) vaccines have been widely used and have been shown to be effective in combating the pandemic. The U.S. Centers for Disease Control and Prevention (CDC) lists common COVID-19 vaccine side effects as pain, swelling or redness at the injection site; fatigue; headaches; muscle pain; chills;. HHS Vulnerability Disclosure, Help by Therefore, to be safe, it's best to wait at least 14 days after you were either diagnosed with Covid-19 or started having Covid-19 symptoms before getting a Covid-19 vaccine. Stroke in Tamsulosin, how severe and when it was recovered? Subacromial bursitis, rotator cuff tendinitis, and glenohumeral arthritis (arthritis of the shoulder joint) are all shoulder conditions that are commonly seen in adults. Arthritis after COVID-19 is a potential complication of the illness. People can develop reactive arthritis after COVID-19. Vaccine. Keeling and Kennedy both emphasized that while SIRVA requires further study, it does appear to be rare, and that the benefits of vaccination against COVID-19 far outweigh any potential risks. Have any problems using the site? https://www.ncbi.nlm.nih.gov/books/NBK499831/, https://www.yourcovidrecovery.nhs.uk/i-think-i-have-long-covid/effects-on-your-body/joint-and-muscle-problems/, https://www.cdc.gov/coronavirus/2019-ncov/long-term-effects/index.html, https://www.niams.nih.gov/health-topics/reactive-arthritis, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9162104/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8831681/, https://www.frontiersin.org/articles/10.3389/fimmu.2022.859926/full. However, we cannot exclude the possibility that the timing of the flare with regard to vaccination was coincidental, SARS-CoV-2 infection has resulted in more than 500000 deaths in the USA and 2500000 worldwide (see the. It can happen if a person develops reactive arthritis due to the inflammation the infection causes. Read on to learn more about how to clear mucus while having COVID-19. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Most pain should eventually go away, but sometimes it might carry on for longer. Note as well that despite the recent full FDA approval for the Pfizer COVID-19 vaccine, any injuries attributed to it at the present time still remain covered under the CICP. Share on Facebook. The HRSA spokesperson said the CICP covers "eligible serious injuries" -- generally, those that require hospitalization or that lead to significant disability. Three months is a . Of the initial COVID-19 claims, the . A BIZARRE new side effect has been reported by people who have received their Covid-19 vaccine. Opens in a new tab or window, Visit us on TikTok. If someone believes they may have long COVID, they should make an appointment with a doctor, who can create a medical management plan for them. Opens in a new tab or window, Visit us on Instagram. Wiesel and Keeling's paper notes that since the VICP was created in the late 1980s for childhood vaccine injury, the demographic has shifted, with more than 50% of claims now involving adults. What is the link between joint swelling and COVID-19? "I just can't move my arm in certain motions," she said. Gulick notes that ear ringing may be triggered after having the virus or getting the vaccine if you have a history of tinnitus and/or a preexisting ear condition. Children and teens ages 6 months-17 years Adults 18 years and older After a second shot or booster "In some patients, the nerves are injured (bright, enlarged) and in others, the problem is impaired blood flow (clots).". The https:// ensures that you are connecting to the The phase IV clinical study analyzes which people get Pfizer BioNTech Covid Vaccine and have Tendonitis. An MRI revealed fluid collecting in his joint, as well as adhesive capsulitis, he said. Meyers says clearly, some people need an attorney to assist. However, his Tweets are now being viewed in a dangerous light, mostly by people attempting to promote anti-vaccination theories. The study found that some patients reported an all-body rashmedically known as a morbilliform rashoften . I got Covid-19 two months ago. Still, most physicians interviewed by MedPage Today say it's likely that improper injection technique could lead to shoulder injury, and that these problems should be taken seriously and treated appropriately. Read more: Questions and Answers for Patients Regarding Elective Surgery and COVID-19. Disclaimer. This is considered an overuse injury caused by repetitive hand or wrist motion. Five years later, SIRVA was added to the Vaccine Injury Table, which guides allowable claims in federal vaccine court. Systemic reactions in persons aged 6-23 months, Pfizer BioNTech BNT162b2 COVID-19 vaccine and placebo a Any fever= 38.0C b Mild: decreased interest in eating; moderate: decreased oral intake; severe: refusal to feed; Grade 4: emergency room visit or hospitalization MB), Help with Byron Jones was the 27th overall pick in the 2015 . References: Mehta N, et al. These can include intra-articular, bursal, tendon . 2022 Jun 30;95(2):217-220. eCollection 2022 Jun. Vaccination infrequently causes severe, persistent . 20052022 MedPage Today, LLC, a Ziff Davis company. 2022 Aug 12;40(34):4964-4971. doi: 10.1016/j.vaccine.2022.06.002. After you get a vaccine shot in your upper arm to protect yourself against the flu, COVID-19, or another disease, there's a chance you'll feel some soreness where you got jabbed. The condition is also plagued by the lack of a solid evidence base, and causality is difficult to pin down. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. Laura Keeling, MD, an orthopedic surgeon at MedStar Georgetown University Hospital in Washington, D.C., told MedPage Today that part of the reason SIRVA remains in the medicolegal realm is that it's "more of a constellation of symptoms and findings" rather than a specific diagnosis. 713-798-4710. A new Northwestern Medicine study has, for the first time, confirmed and illustrated the causes of these symptoms through radiological imaging. Epub 2021 May 4. Common reactions include: True allergic or life-threatening reactions following vaccination are extremely rare. Financial support for ScienceDaily comes from advertisements and referral programs, where indicated. Content on this website is for information only. It says musculoskeletal symptoms, such as joint pain and muscle pain, are among a number of common possible long Covid signs. Generally, it's characterized as a "constellation of shoulder pain and reduced range of motion that occurs within 48 hours of vaccination and does not resolve within 1 week," according to a recent paper Keeling co-authored. A statement from Johnson & Johnson said that tinnitus was identified as an adverse event in its phase 3 clinical trials of the Covid-19 vaccine but also maintained that it was impossible to. This resource was created to help address concerns you may have about the effect of the COVID-19 vaccine on your musculoskeletal health. an abnormal one at injection site), Injection site paraesthesia (abnormal skin sensations at injection site), Injection site pruritus (severe itching at injection site), Injection site urticaria (rash of round, red welts on the skin at injection site), Injection site vesicles (fluid- or air-filled cavity or sac at injection site), Ischaemic stroke (stroke; caused by an interruption in the flow of blood to the brain), Joint range of motion decreased (disease of joint movement), Leukocytosis (increased white blood cells), Lung infiltration (a substance that normally includes fluid, inflammatory exudates or cells that fill a region of lung), Lymphadenitis (inflammation or enlargement of a lymph node), Lymph follicular hypertrophy (an increase in the size of the lymph node follicles), Lymphoedema (localized fluid retention and tissue swelling), Malaise (a feeling of general discomfort or uneasiness), Mastication disorder (disease of chewing food), Maternal exposure during pregnancy (use of substance during pregnancy), Menstrual disorder (disease of menstrual cycle), Menstruation delayed (late menstruation cycle), Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability), Mental impairment (a condition affecting the body, perhaps through sight or hearing loss, a mobility difficulty or a health condition), Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation), Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy), Middle ear effusion (fluid in middle ear), Migraine with aura (headache with vision weakness), Mitral valve incompetence (inefficient heart valve), Mobility decreased (ability to move is reduced), Monoplegia (a paralysis of a single limb), Mood swings (an extreme or rapid change in mood), Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness), Multiple sclerosis (a nervous system disease that affects your brain and spinal cord. Is there a link between overactive bladder and COVID-19? Some patients may experience side effects after vaccination, but these are typically mild and go away in a few days. Radiol Case Rep. 2021 Dec;16(12):3631-3634. doi: 10.1016/j.radcr.2021.08.019. (2022). The incidence of post-COVID-19 arthritis was 37%. However, 1530% of people may develop long-term arthritis and other joint issues. Materials provided by Northwestern University. Recap. The .gov means its official. The study is based on data from the CDC and the FDA. For these reasons, you should continue to wear a mask, practice social distancing, avoid crowds and wash your hands often. It is created by eHealthMe based on reports of 401,887 people who have side effects when getting Pfizer BioNTech Covid Vaccine from the CDC and the FDA, and is updated regularly. Although the mechanism of flare is not known, one could speculate that one of these components might have had non-specific adjuvant effect, or there could have been molecular mimicry between the viral spike peptides and the patient's self-peptides, activating a flare. Opens in a new tab or window, Share on Twitter. Common reactions include: Swelling or redness at the site of the injection Systemic reactions, such as fever, chills, nausea, vomiting, muscle aches, or fatigue This may help reduce symptoms and increase quality of life. Reports of people experiencing tinnitus, vertigo and other hearing problems after having COVID-19 started emerging earlier in the pandemic. If even after 4-6 months post Covid, you are having persistent pain it needs to be investigated If the patient suffered from autoimmune arthritis then a rheumatologist must be involved While. This site needs JavaScript to work properly. SIRVA (Shoulder injury related to vaccine administration) following mRNA COVID-19 Vaccination: Case discussion and literature review. COVID-19; Calcific tendinitis; mRNA; shoulder injury related to vaccine administration; vaccine. Yes, COVID-19 can trigger arthritis in some people. As a veterinarian, Jackson is well versed in giving injections: "This was just poor administration technique," she told MedPage Today. Subacromial-subdeltoid bursitis following COVID-19 vaccination: a case of shoulder injury related to vaccine administration (SIRVA). Sometimes surgery is needed to treat an underlying pathology such as an exacerbated rotator cuff injury. 2 cm deep to the quadriceps tendon and involved the medial and lateral gutter (, Arthrocentesis of the right knee showed 24 mL of inflammatory-appearing effusion (, His rheumatoid arthritis was well controlled before the vaccination, and there were no other inciting events, so we believe that this flare might have been triggered by his immune response to a component of the BNT162b2 vaccine. Northwestern University. "Pending establishment of COVID-19 Countermeasures Injury Table, claims may be filed as non-Table injuries and eligibility for compensation will be determined on a case-by-case basis by the Program," the spokesperson said. Shoulder injury related to vaccine administration, or SIRVA, has been documented long before COVID-19 vaccination, and is most frequently reported after influenza vaccination. The symptoms of reactive arthritis include inflammation, swelling, and pain in the joints. This information is provided as an educational service and is not intended to serve as medical advice. The New York City-based veterinarian said the nurse lodged the shot "extraordinarily high" into her left shoulder, hitting the bursa rather than the deltoid muscle. According the ZOE Covid symptom study released last month and looking only at the Pfizer jab, about a third of vaccine recipients who had previously had Covid reported having a whole-body side . Many patients who have had the virus have a positive antibody test. If symptoms persist, surgery to remove a spur on the acromion can increase the space available for the inflamed tendon and may prevent further fraying or complete rupture. Radiographs showed calcification of the supraspinatus tendon, and magnetic resonance images showed continuous inflammatory findings from the subdeltoid bursa to the subacromial bursa. Her primary care doctor referred her to a physical medicine & rehabilitation specialist who, after confirming bursa and joint inflammation on imaging, prescribed steroid and lidocaine injections along with physical therapy. COVID-19 vaccines produce an antibody reaction that protects you from the disease. Dr. Even going to a toilet has its risks. In females, this can lead to inflammation in the genital and reproductive organs as well. People with inflammatory or autoimmune arthritis may be at greater risk of contracting COVID-19 and developing more severe symptoms than others. 5. Fatigue (feeling of tiredness): 25 people, 13.89%, Mobility Decreased (ability to move is reduced): 17 people, 9.44%, Arthritis (form of joint disorder that involves inflammation of one or more joints): 16 people, 8.89%, Muscle Aches (muscle pain): 15 people, 8.33%, Hypoaesthesia (reduced sense of touch or sensation): 14 people, 7.78%. For weeks, she had severe pain that didn't respond to over-the-counter anti-inflammatory medications. It also examines joint pain with long COVID and flare-ups in preexisting arthritis. The pain largely resolved but returned, albeit to a lesser extent, after 6 weeks, and a follow-up MRI confirmed persistent bursa inflammation. Skin reactions to the COVID vaccine aren't just limited to where you get your jab. Symptoms from improperly administered vaccinations - known as SIRVA, for "shoulder injury related to vaccine administration'' - include chronic pain, limited . But for some people, symptoms are more severe, long lasting and even bizarre, including rheumatoid arthritis flares, autoimmune myositis or "COVID toes.". Is the ketogenic diet right for autoimmune conditions? With the emergence of the rapidly spreading omicron variant, COVID-19 booster shots are now strongly recommended by the Center for Disease Control and Prevention. If you develop tinnitus after your COVID-19 vaccine, report it to VAERS. You can learn more about how we ensure our content is accurate and current by reading our. If you are having a corticosteroid injection for an orthopaedic condition, such as arthritis or carpal tunnel syndrome, your doctor may advise you to wait for a few days after the injection before receiving the COVID-19 vaccine. But I do think it's possible, absolutely" for vaccine-related shoulder injury to occur. Published by Oxford University Press. Joint pain may also be present in long COVID. The use of the eHealthMe site and its content is at your own risk. Also, even though the vaccine helps protect you from getting sick, it is not known if you could still be a carrier of the virus. Chills. Pain and reduction in the range of movement within a few hours of vaccination were cardinal signs of a shoulder injury. Kristina Fiore leads MedPages enterprise & investigative reporting team. The vaccines that have been developed to protect against COVID-19 differ from traditional vaccines in that they do not inject a live or deactivated virus into the body. "I have previous tests to prove . it causes swelling, ulcerations, and loss of function of the large intestine), Urinary incontinence (inability to control the flow of urine and involuntary urination), Urinary retention (the inability to completely or partially empty the bladder), Urticaria (rash of round, red welts on the skin that itch intensely), Vaccination site erythema (redness around vaccination site), Vaccination site pruritus (severe itching of the skin at vaccination site), Vasculitis (inflammation of a blood vessel or blood vessels), Ventricular extrasystoles (premature cardiac contraction), Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart), Vitreous floaters (spots before the eyes), Weight bearing difficulty (difficulty due to weight of thigh fat deposition), Wheezing (a high-pitched whistling sound made while you breath). Research suggests that overactive bladder and COVID-19 have links. The paper will be published Feb. 17 in the journal Skeletal Radiology. The CDC recommends that you have the COVID-19 vaccine even if you have had an allergic reaction to food, oral medications, pets, or environmental toxins, such as dust or latex, in the past. Uncertainty persists as to the possibility that the COVID-19 vaccines might cause exacerbation of pre-existing autoimmune diseases. Fewer people should get sick, and more lives can be saved. Rotator Cuff and Shoulder Conditioning Program, The COVID-19 Vaccine and Your Bones and Joints. This website also contains material copyrighted by third parties. Treatment for tendonitis and tenosynovitis Treatment may include: Changing your activities Icing the area to reduce inflammation and pain Putting a splint on the area to limit movement Steroid injections to reduce inflammation and pain Nonsteroidal anti-inflammatory medicine to reduce inflammation and pain Antibiotics if due to infection Surgery One of these conditions is rheumatoid arthritis (RA). They can vary across different age groups. According to the federal Vaccine Adverse Event Reporting System (VAERS) [1], there were 21 deaths this flu season after 180+ million flu vaccines, a rate of 1 death per 9,000,000 vaccinations. ScienceDaily. We declare no competing interests. Many orthopaedic patients have questions about how the COVID-19 vaccine might impact theirbones and joints. Tendonitis (a condition that causes pain and swelling of tendons) is found to be associated with 1,831 drugs and 1,232 conditions by eHealthMe. All rights reserved. "COVID-19 causes a variety of neurological symptoms, which can stay behind in a patient after initial recovery or can develop later," said Dr. Sanghavi. People may mistake these symptoms for arthritis. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Learn. Tendonitis in Johnson & Johnson COVID Vaccine, Abortion spontaneous (naturally occurring miscarriage), Acute myocardial infarction (acute heart attack), Acute upper airway obstruction (blockage occurs in the upper airway), Ageusia (loss of taste functions of the tongue), Agitation (state of anxiety or nervous excitement), Alopecia areata (patchy baldness that typically begins with rapid hair loss), Anaphylaxis (serious allergic reaction that is rapid in onset and may cause death), Angioedema (rapid swelling of the dermis), Appendicitis (inflammation of the appendix), Appetite - decreased (decreased appetite occurs when you have a reduced desire to eat), Appetite - increased (increased appetite is when you want to eat much more often or in larger quantities than your body requires), Ards (acute respiratory distress syndrome) (sudden failure of the respiratory (breathing) system), Arthritis (form of joint disorder that involves inflammation of one or more joints), Asthenopia (eyestrain-tiredness of the eyes caused by prolonged close work by a person with an uncorrected vision problem), Atelectasis (partial or complete collapse of the lung), Atrial fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles), Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue), Autonomic nervous system imbalance (autonomic nervous system is of net equal emphasis), Basedow's disease (autoimmune disease where the thyroid is overactive, producing an excessive amount of thyroid hormones), Belching (release of gas from the digestive tract), Blindness transient (sudden loss of vision), Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure), Blood thyroid stimulating hormone decreased, Blood thyroid stimulating hormone increased, Bradycardia (abnormally slow heart action), Breast lump (localized swelling that feels different from the surrounding breast tissue), Bronchitis (inflammation of the mucous membrane in the bronchial tubes), Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle), Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder), Canker sores (painful, open sore in the mouth), Cardiomyopathy (weakening of the heart muscle), Cardio-respiratory arrest (sudden dysfunction of heart and lungs), Cerebral haemorrhage (bleeding within the brain), Cerebral infarction (less blood supply to brain resulting tissue damage), Cerebral thrombosis (blood clot in brain), Chapped lips (cracking, fissuring, and peeling of the skin f lip), Chronic obstructive pulmonary disease (a progressive disease that makes it hard to breathe), Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving), Concussion (short loss of normal brain function in response to a head injury), Coronary artery occlusion (complete obstruction of blood flow in a coronary artery), Coronary heart disease (narrowing or blockage of the coronary arteries), Crohn's disease (condition that causes inflammation of the gastrointestinal tract), Deep venous thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis), Dehydration (dryness resulting from the removal of water), Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it), Dermatitis contact (skin reaction (dermatitis) resulting from exposure to allergens), Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies), Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall), Drooling (drop saliva uncontrollably from the mouth), Dyskinesia (abnormality or impairment of voluntary movement), Ear pruritus (pruritus or itching is ""the unpleasant skin sensation that frequently provokes scratching"" in ear), Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters), Ejection fraction (the percentage of blood that is pumped out of a filled ventricle as a result of a heartbeat), Ejection fraction decreased (systolic heart failure), Encephalopathy (functioning of the brain is affected by some agent or condition), Euphoric mood (excessively happy but may become angry or irritable), Eyelid ptosis (falling of the upper or lower eyelid), Eyelid twitch (spontaneous and uncontrolled spasms of the muscles), Facial paralysis (loss of function of face muscle), Facial paresis (weakness in facial muscle movement), Fainting (loss of consciousness and postural tone), Feeding disorder (when children refuse to eat certain food groups), Fibromyalgia (a long-term condition which causes pain all over the body), Flank pain (a distressing sensation experienced around the lower back and the upper abdomen), Flatulence (flatus expelled through the anus), Fluid retention (an abnormal accumulation of fluid in the blood), Formication (a sensation that exactly resembles that of small insects crawling on (or under) the skin), Gastroesophageal reflux disease (a condition in which stomach contents leak backward from the stomach into the oesophagus), Gastrointestinal disorder (functional problems of gastrointestinal tract), Gastrointestinal haemorrhage (bleeding gastrointestinal tract), Gaze palsy (disorders affecting the ability to move both eyes in the same direction), General physical health deterioration (weak health status), Glossodynia (a burning or painful sensation in the tongue), Gout (uric acid crystals building up in the body), Guillain-barre syndrome (the body's immune system attacks its peripheral nervous system), Haematochezia (passage of stools containing blood), Haematoma (collection of blood outside the blood vessels), Hallucinations (sensations that appear real but are created by your mind), Heart palpitations (feelings or sensations that your heart is pounding or racing), Hemiparesis (weakness on one side of the body), Hemiplegia (paralysis of one side of the body), Herpes simplex (herpes simplex is a common viral infection), Hyperacusis (disorder in loudness perception), Hyperhidrosis (abnormally increased sweating), Hyperkalemia (damage to or disease of the kidney), Hyperthyroidism (over activity of the thyroid gland), Hypervolaemia (abnormally increased volume of blood), Hypoaesthesia (reduced sense of touch or sensation), Hypoaesthesia oral (reduced sense of touch or sensation in mouth), Hyponatremia (abnormally low level of sodium in the blood; associated with dehydration), Hypotension (abnormally low blood pressure), Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development), Idiopathic pulmonary fibrosis (chronic lung disease), Incoherent (talking in a confused and unclear way), Incontinence (lack of moderation or self-control), Injection site erythema (redness at injection site), Injection site haemorrhage (bleeding from injection site), Injection site nodule (small swelling or aggregation of cells in the body, esp.