A comparative clinical study investigating the efficacy of a dentifrice containing 8% strontium acetate and 1040 ppm fluoride in a silica base and a control dentifrice containing 1450 ppm fluoride in a silica base to provide immediate relief of dentin hypersensitivity. 3 Report Deon Hines-0003, 2016. However, the manufacturers of the tested dentifrices were acknowledged in the study [34], so information bias wasexpected in the conducted trial. Martins C, Firmino R, Riva J, Ge L, Carrasco-Labra A, Brignardello-Petersen R, et al. Colgate Sensitive Pro Relief Multi Protection, offering all of the above benefits in one convenient formula. Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. Helps repair teeth by forming a mineral layer that re-constructs the sensitive part of the tooth, with regular use; Seals the open nerve channels for instant relief, and helps prevent sensitivity from re-occurring; Plus the freshness you trust from Colgate 3. * For instant relief, apply directly to the sensitive tooth with finger tip and gently massage for 1 minute. There is no problem with every day and prolonged use. Colgate SENSITIVE Instant(Pro) Relief Enamel Repair Toothpaste 75ml (Pck 4,6,12) 15.99 to 39.99. Comparative evaluation of desensitizing efficacy of dentifrice containing 5% fluoro calcium phosphosilicate versus 5% calcium sodium phosphosilicate: a randomized controlled clinical trial. They reported more clinical efficacy with BioMin than Pro-argin reduction in air-blast stimulated DH on VAS after one month [39]. The widely accepted hydrodynamic theory proposes that stimuli can alter the behavior of fluid in the dentin tubules, activating intra-dental nerve fibers and causing pain. We discuss how this innovative technology works to provide patients with rapid and long-lasting relief from dentin hypersensitivity. J Clin Dent. Identifier NCT 04249336. Dentin hypersensitivity is characterized by a short, sharp pain arising from open dentin tubules in exposed dentin in response to external stimuli, which cannot be attributed to any other defect or disease. A head-to-head comparative evaluation of these most effective bioactive agents, such as arginine and BAG-based desensitisers, was suggested by Martins et al. IADR, The Excel, United Kingdom. 1Intervention for Group A denotes BioMin F. 2Intervention for Group B denotes Colgate Sensitive Pro relief. Pak Oral Dent J. Colgate Sensitive Pro Relief Teeth Whitening Sensitivity Toothpaste, 75ml 4.9 out of 5 stars 12 7 offers from SAR 33.95 Colgate Sensitive Pro Relief Base Instant Sensitivity Relief Toothpaste, 75ml 4.3 out of 5 stars 20 5 offers from SAR 31.25 Colgate Total 12 hour Protection Pro - Gum Health Toothpaste 75ml Felix J, Ouanounou A. Dentin hypersensitivity: etiology, diagnosis, and management. Clinically proven amino acid formula with Pro-Argin technology to provide sensitivity relief. # In-vitro study, actual confocal images after 5 treatments. Colgate Sensitive Pro-Relief r en tandkrm som ger omedelbar och varaktig lindring mot ilningar i tnderna. 2010;11:32. The sealed envelope contained details of unique subject numbers assigned individually in ascending order, group titles, and treatment codes and was placed in the box. For patients in the dental chair, it can be used to rapidly ease hypersensitivity pain, facilitate examinations and make dental procedures more comfortable. Table 3 demonstrates the percent change in the mean scores of DH on SCASS relative to baseline within the group for each treatment arm. . Tel: +381 (0)21 452-910, +381 (0)21 420-758. Therefore, the current study outcomes were analysed by parametric and non-parametric statistical tests after assessing the normal distribution of data and equality of variances with Shapiro Wilk statistics. 2017;2017:2. 2017;30(4):2216. YES Somewhat No Dent Health Curr Res. All participants were instructed to dry the tooth surface with the cotton ball and apply a paste of about half-inch length on the dried surface for one minute, then brush the teeth twice daily after breakfast and before sleep as per directions demonstratedon the study model. The Pro-Argin technology repairs sensitive areas of the teeth for instant* and long-lasting sensitivity pain relief. West N, Newcombe RG, Hughes N, Mason S, Maggio B, Sufi F, et al. Read our disclaimer for details. https://doi.org/10.17352/2394-8418.00003. J Evid Based Dent Pract. who examined FCPS and Pro-argin formulations in 2018. Aust Dent J. There was no statistically significant treatment difference between the two (p=0.499). 2010;21(2):428. We found more change in pain scores of VAS used for mechanical stimuli with Pro-argin than FCPS as shown in Table 5 that could be relatable with a randomised controlled trial of FCPS and arginine based desensitizers reporting better treatment response of arginine than FCPS in the cold stimulated DH after two weeks to one month, subsequently [40]. Mintsmak. With regular use, the Pro-Argin formula builds a long-lasting protective barrier that acts like a seal against sensitivity. Both treatments showed clinically and statistically significant (p<0.001) relief in pain due to DH relative to baseline on immediate post-treatment observation, as shown in Table 3. Venkataramana S, Jeyaraman SK, Kothimbakkam SSK, Chellathurai BNK. In our study, patient compliance related to the recommended time of application and method of the application provided by doctors was controlled by subjecting multiple efficacy intervals and different methods for assessment of the change in pain scores due to DH. The burden of dentine hypersensitivity. * with direct application and daily brushing Benefits Exclusive Pro-Argin formula Prevents sensitivty coming back Trials. blokerer jeblikkeligt smerter fra isninger. How does Colgate Sensitive Pro-Relief Repair & Prevent work? 2018. Dentin hypersensitivity (DH) is a sharp toothache that influences a patients' oral health-related quality of life. Yang ZY, Wang F, Lu K, Li YH, Zhou Z. Arginine-containing desensitizing toothpaste for the treatment of dentin hypersensitivity: a meta-analysis. See patient relevant information on Colgate.com. J Dent. Google Scholar. Wilcoxon Signed-Rank Test was used to compute mean scores relative to baseline at each time point. Participants were recalled at interim efficacy intervals of three days, two weeks, four weeks, and six weeks for assessment of sustained relief. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. If symptoms persist, talk to your healthcare professional. Colgate Sensitive Instant Relief Whitening Toothpaste 75 ml Pack of 5, Blocks Pain Instantly, Prevents Sensitivity, Gently Removes Stains (5 x 75 ml) 1,230 5 offers from 12.50 Colgate Sensitive Pro Relief Enamel Repair Toothpaste 75ml - 4 packs 94 22 offers from 14.14 Colgate Sensitive Instant Relief Enamel Repair Toothpaste 75 ml 190 Network meta-analysis on the effect of desensitizing toothpastes on dentine hypersensitivity. With its unique Pro-Argin technology, this sensitive toothpaste will give you instant* relief from sensitivity as it helps to seal and repair the sensitive areas of your teeth. Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste for the daily oral care of patients with dentine hypersensitivity and gum problems. Therefore, this trial was planned to investigate the clinical efficacy of Pro-argin and strontium acetate for immediate pain relief in DH after one minute of topical application to fill the research gap associated with limited published evidence and risk of bias in selection, performance, attrition, and reporting as predicted by Pessoa et al. Mantzourani M, Sharma D. Dentine sensitivity: past, present and future. 90 sold. Colgate Toothpaste relieves the discomfort of tooth irritation by still addressing the root causes. Colgate Sensitive Pro Relief was compared to a leading brand of desensitizing toothpaste containing stannous fluoride in a laboratory study, with confocal laser scanning microscopy and a novel imaging program used to qualify dentinal tubule occlusion. Mahmoodi B, Wood R, Cook R. Protection and acid resistivity of bioactive-glasses, arginine and calcium silicate. Dentine tubule occlusion by novel bioactive glass-based toothpastes. Shiau HJ. Written consent was obtained from all participants to participate in the six-week clinical trial. Dent Health Curr Res. We were using the PAS version.11, two independent sample t-test with 95% confidence interval and 80% power of test, meanSD of air blast stimulus test score of test group 1.860.41 and control group 2.220.41 two weeks after baseline test score, the calculated sample size was 22 [21] which was raised to 35 including five as drop out for each group (Fig. Dentin hypersensitivity treatments work in one of two ways. * *With continued use twice a day Prevents sensitivity from coming back* *With continued use twice a day can help prevent sensitivity from coming back. Colgate Sensitive Pro Relief can be applied directly to the affected area for almost instant relief. In addition, they were responding to air-blast stimulus on the Schiff cold air sensitivity scale (SCASS) with scores2 [22]. Dentine hypersensitivity. Colgate Sensitive Instant Relief Repair & Prevent tandkrm ger dig kliniskt bevisad lngvarig lindring mot ilningar i tta veckor nr du anvnder den tv gnger om dagen. A total of 128 participants completed the trial. Gillam D, Talioti E. The Management of Dentine Hypersensitivity. ClinicalTrial.gov: National Library of Medicine (US). compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. The Colgate Sensitive Pro Relief range features toothpastes that provide relief for sensitive teeth while addressing other common oral health concerns: Colgate Sensitive Pro Relief Repair and Prevent to protect against gingival recession. * For instant relief apply to the sensitive tooth with a figure tip and gently massage for one minute. J Clin Periodontol. Pro-Argin showed a greater reduction in DH with mean scores of (1.340.68) (4.201.70) (3.052.17) followed by strontium acetate (1.570.81) (4.651.87) (3.751.97) on SCASS and VAS for mechanical and water jet stimuli, one minute after application. Therefore, it was considered to be rejected at a p valueof 0.05. https://doi.org/10.1186/s12903-021-01864-x, DOI: https://doi.org/10.1186/s12903-021-01864-x. It was measured by assaying change in SCASS scores of pains with Pro-argin and 8% strontium acetate after one minute of topical application on the sensitive teeth. 0. 2010;21(2):568. 75 ml. It was found statistically significant relative to control on all clinical parameters of the SCASS and VAS. Benefits: Colgate Sensitive Prevent and Repair is clinically proven to provide superior relief vs Sensodyne Extra Whitening at 8 weeks1 Long-lasting relief from hypersensitivity with continued use Superior sensitivity relief at 8 weeks vs the leading Sensodyne toothpaste variant 1 Post-hoc analysis revealed a significant reduction in DH scores in treatment arms compared to control on completing the six-week trial (p<0.05). 2019;88:103170. p values of<0.05 were considered as statistically significant. Colgate Sensitive Pro-Relief Multi Protection Toothpaste provides clinically proven instant and lasting relief for sensitive teeth For instant relief, apply directly to each sensitive tooth with finger tip and gently massage for 1 minute, up to twice daily Oral dentifrices have been marketed extensively for pain relief in one minute after topical application on sensitive teeth, with the claims of several dentists recommending the formulations containing Pro-argin and 8% strontium acetate. fluorides, arginine, strontium, and bioactive glasses (BAG) [4] and in-office application of bioactive formulations such as glutaraldehyde, resin-based bonding agents and restorative materials, amorphous calcium phosphate based-tooth mousse, and lasers in the dental clinics [5]. Google Scholar. PREVENTS SENSITIVITY COMING BACK: Sealed channels protect against pain for instant relief, and with regular use provide lasting protection to prevent sensitivity from . This site is intended for healthcare professionals only. Article The comparative evaluation was done for the clinical efficacy of Pro-argin and 8% strontium acetate, and a statistically significant (p>0.05) difference was not found between these two formulations in the current study. However, strontium acetate can potentially obliterate dentinal tubules by replacing the calcium ions of hydroxyapatite crystal lattice structure withstrontium ions along with its nerve depolarisation treat DH [7]. Helps restore natural whiteness of teeth. Yes, Colgate SENSITIVE INSTANT Relief Repair & Prevent Toothpaste should be used for twice daily toothbrushing to provide ongoing relief from the pain of sensitive teeth. The study's primary objective was to investigate pain relief in one minute with Pro-argin and strontium acetate in DH measured on SCASS as a primary outcome measure and VAS as a secondary outcome measure. Ingredients *Potassium Nitrate Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. There was a significant (p<0.001) reduction of 45.7% with Pro-argin, 37.6% with 8% strontium acetate, 18.1% with FCPS, and 15.2% with NaF-based dentifrices relative to baseline on SCASS after one-minute application on sensitive teeth. compared the Pro-Argin formulation with a calcium sodium phosphosilicate toothpaste, demonstrating 88% versus 50% occlusion respectively. 2017;59(4):4618. 2017;2017:2. Colgate Sensitive Pro-Relief Enamel Rebuild also: Fights cavities Strengthens enamel Freshens breath Vegan . Hu et al. Product Details For instant relief, apply directly to the sensitive tooth with finger tip, and massage gently for 1 minute, once a week or less frequently. Am J Dent. statement and Statistical Package for the Social Sciences software v.21.0. According to Holland's guidelines of conducting a trial for managing DH, two diagnostic tools are sufficient for quantitative assessment of the clinical efficacy of desensitisers. Madurai: Best Dental Science College; 2020. For lsting relief, apply to a gentle toothbrush making sure to brush all . When it begins to interfere with oral hygiene, it can also lead to poor oral health outcomes. The limitation of our study is that fluoridated dentifrice was used as a control which, although regarded as not possessing any desensitising effects. WAF has contributed to revising the manuscript critically and contributed to statistical analyses. Help Caregivers Understand Caries | Colgate Professional, compared to a leading brand of desensitizing toothpaste, Colgate Sensitive Pro Relief Repair and Prevent, Colgate Sensitive Pro Relief Enamel Repair, Colgate Sensitive Pro Relief Multi Protection. Ingredients *Calcium carbonate *Water Part of [28] reporting the immediate effect of 8% strontium acetate in alleviating clinical symptoms of DH with clinically and statistically significant (<0.001) measures relative to baseline [26]. Compend Contin Educ Dent. No side effects, apart from money not well spent. Colgate Professional has resources to help your patients understand what causes enamel erosion and how to avoid falling into those traps. 2016;8:114. Colgate Sensitive Pro Relief Enamel Repair to strengthen weakened enamel and prevent enamel loss. 2016;3(1):0504. Find products and services. J Non Cryst Solids. For instant relief, just apply directly to the sensitive tooth with finger tip and gently massage for one minute. 3rd edition, Public Health England 2014. Schiff T, Delgado E, Zhang Y, Cummins D, DeVizio W, Mateo L. Clinical evaluation of the efficacy of an in-office desensitizing paste containing 8% arginine and calcium carbonate in providing instant and lasting relief of dentin hypersensitivity. In vitro analysis suggested that FCPS-based dentifrice enabled the slow and sustained release of fluoride contents, resulting in more stable fluorapatite crystals in saliva [14, 15]. Desensitizing toothpastes for dentin hypersensitivity: a network meta-analysis. Colgate SENSITIVE INSTANT Relief tannkrem med Pro-Argin teknologi gir umiddelbar* og langvarig smertelindring av ising i tennene. Results of our study, together with the results of the previous studies, confirm the immediate clinical efficacy of Pro-argin for the relief of DH. Participants were asked to pick up the envelope from the box. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Colgate SENSITIVE INSTANT Relief Repair & Prevent toothpaste with PRO-ARGIN Technology and Zinc provides clinically proven instant* and lasting sensitivity relief1-2 plus lasting gum protection3. In addition, one-Way ANOVA with Post Hoc Tukey for pair-wise comparison was used to compare treatment groups computing percent change from baseline with formula (post-application mean scores-baseline mean scores/baseline mean scores). SCASS and VAS were introduced on each visit as primary and secondary outcome measures, respectively. Another . Dziki unikalnej formule Pro-Argin z arginin, wzmacnia szkliwo zbw i tym samym staj si one bardziej odporne na dziaanie kwasw. J Clin Periodontol 42 (2015), 17, 4. 1,2 Lai HY, Lee S, Toh SW, Li Y, Mateo LR, Morrion BM, Zhang Y: The clinical efficacy of a new dentifrice with zinc on plaque and gingivitis. Mason S, Hughes N, Sufi F, Bannon L, Maggio B, North M, et al. Two double-blind randomized clinical studies by Nathoo et al. Frequency of dentin hypersensitivity: a cross-sectional study. J Oral Rehabil. 7 Ipsos, UK Patient Experience Programme on Colgate SENSITIVE PRO-Relief, results collected after 2 weeks trial, 192 respondents, 2016. Colgate Sensitive Pro Relief Whitening Toothpaste 75ml tube (Pack of 4) Instant and Lasting Relief Clinically Proven with Active Ingredients We have a surprise for you Find out all personalised promo codes that you are eligible for. J Clin Dent. DH most commonly involves the facial surfaces of maxillary and mandibular permanent teeth. Holland GR, Narhi MN, Addy M, Gangarosa L, Orchardson R. Guidelines for the design and conduct of clinical trials on dentine hypersensitivity. Dentifrices-containing Pro-argin showed a significant reduction in DH with mean scores of (3.052.17) followed by strontium acetate (3.751.97) followed by FCPS (5.301.83) one minute after application. The second objective of the current study was to directly compare the clinical efficacy of FCPS, Pro-argin technology, and strontium acetate-based dentifrices due to their similar mode of action and tubular occluding potential in managing DH [36, 37]. It remains a prevalent global disease with two different treatment modalities of home-care desensitisation with the over-the-counter (OTC) desensitisers such as potassium, These ingredients resulted in rapid fluorapatite crystallisation at exposed tubular ends of dentin [12]. Colgate Sensitive Instant Relief Enamel Toothpaste with Pro-Argin technology to help seal and repair the sensitive areas of teeth. Google Scholar. Colgate Sensitive Plus Toothpaste developed for sensitive teeth provides sensitivity protection And helps in Enamel Repair, Cavity . While your patients may have dentine hypersensitivity in common, their oral care needs will vary. Treatment difference between FCPS, Pro-argin, and 8% strontium acetate was not statistically significant with a p>0.05 for sustained pain relief in DH. Explore the videos and articles found on this page to assist in better oral care. The price for Colgate Sensitive Pro-Relief is set at RM12.80 to avoid being categorized at RM13.00. Provides 24/7 sensitivity protection. Balevi B. For lsting relief, apply to a gentle toothbrush making sure to brush all sensitive areas of the teeth twice daily. Arginine, Calcium Carbonate, Aqua, Sorbitol, Aroma, Poloxamer 407, Sodium Monofluorophosphate, Cocamidopropyl betaine, Zinc oxide, Benzyl Alcohol, Cellulose Gum, Zinc Citrate, Sodium Bicarbonate, Tetrasodium Pyrophosphate, Xantham Gum, Sodium Saccharin, Sucralose, Limonene, CL77891, 1. Friedman Test was used to observe post-application change in treatment responses within the group for 6weeks. Colgate Sensitive Pro-Relief Instant Relief Sensitive Toothpaste - 75ml More Images Colgate Sensitive Pro-Relief Instant Relief works as a shield that blocks pathways to pain instantly. In contrast, there was a significant (p<0.001) reduction of 61.1% with FCPS, 60.1% with Pro-argin, 53.4% with 8% strontium acetate, and 25% with NaF-based dentifrices relative to baseline after subsequent six weeks of application observing sustained relief from DH on SCASS. Free postage. Cunha-Cruz J, Wataha JC. YYYY Colgate-Palmolive Company. The arginine, calcium carbonate and phosphate plug created by Colgate Sensitive Pro Relief remains intact with ongoing use, even when exposed to acid challenges. While 8% strontium acetate showed a greater clinical reduction in water jet stimulated DH on VAS than Pro-argin at all efficacy intervals, as demonstrated in Table 6. The statistician was also kept blinded. Colgate Sensitive Instant Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*. Moreover, FCPS as a new bioactive material revealed promising potency of sustainable management of DH in a previously conducted trial by Ashwini et al. 75 ml. Am J Dent. Colgate Sensitive Pro-Relief works by plugging the channels to block tooth sensitivity and with regular use, it builds a long-lasting protective barrier that acts like a seal against sensitivity. Douglas-de-Oliveira DW, Vitor GP, Silveira JO, Martins CC, Costa FO, Cota LOM. in 2018 [17]. These participants were randomized equally by the principal investigator into four entitled treatment arms using computer-generated random sequence numbers, and treatments were allocated randomly using sequentially numbered, opaque, sealed, and stapled envelopes (SNOSE). 2 Docimo et al. We observed the varying treatment response at different efficacy intervals that could be due to the varying degree of patient's response to pain-provoking stimuli in DH. Individuals either with dental caries, heavily restored, or cracked teeth, or with orthodontic or prosthetic appliances, or with localised or generalised gingivitis or pulpitis and heavy calculus or using any desensitising toothpaste or mouth wash or any other desensitising products up to six weeks before the study were excluded from this trial. J Dent. and Ayad et al. Colgate-Palmolive Company 2018. Follow the directions for use. The New Colgate Sensitive Instant* Relief Repair & Prevent Toothpaste starts blocking sensitivity pain instantly*.
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